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Doctors usually begin with a low dose of semaglutide, such as 0.25 mg, given once a week as a subcutaneous injection

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From there, the trial product estimand and the treatment policy estimand were used to assess the efficacy of the treatment in all randomly assigned participants

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The medication should be discontinued at least 2 months before planned pregnancy due to long half-life

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Expired injectables also pose infection risk if sterility has been compromised

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